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How do I convert the ATTAIN-1 hazard ratio into an absolute risk reduction?

Asked 4 Apr 2026Modified 4 months agoViewed 6.9k times
21

I have the full paper rather than the abstract, and the supplementary appendix.

I would rather understand the derivation than memorise the outcome.

Two people I asked gave two answers that differ by a factor of ten, which is suggestive.

Can someone show the working rather than just the answer?

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askedrania_haddad17k284 Apr 2026
4The arithmetic checks out. I ran the same numbers and got the same result. – claudia_ferrante 4 months ago
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This question has not been answered. It has been viewed 6.9k times, which suggests the question is of interest and the answer is not obvious. If you can answer it with a source or a worked calculation, it will be read. See how to ask and answer.
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