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needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle syringe behaves differently from a luer-lock one.

85 questions · sorted by votes · page 1 of 4

41 votes 5 answers46k views
Is a 31G needle the right choice for drawing survodutide at 8 mg/mL?

The particulars: a 31G needle · survodutide · 8 mg/mL. I am trying to choose between two options that are usually discussed as though only one exists. I am not…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by Dr_Elias_Weiss 46k · 20 months ago
41 votes 5 answers28k views
Is a 31G needle the right choice for drawing ecnoglutide at 2 mg/mL?

The specifics, since they change the answer: a 31G needle · ecnoglutide · 2 mg/mL. The comparison I want does not seem to exist anywhere in a form I can evaluate. I…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by zeynep_arslan 20k · 22 months ago
40 votes0 answers37k views
Is a 27G needle the right choice for drawing a GLP-1 receptor agonist at 4 mg/mL?

Stated plainly: a 27G needle · a GLP-1 receptor agonist · 4 mg/mL. I suspect the honest answer is that it depends, in which case I would like to know on what. Assume…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by jonas_ekstrom 18k · 2.2 years ago
38 votes 5 answers70k views
Should I use a 25G drawing needle to draw and something finer to administer?

For context, I am working with a 10 mg presentation and a 2 mL fill. This is a procedural question rather than a theoretical one, and I would like the procedure…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
sterility
sterility

Sterility as a test result rather than an adjective. Covers what a sterility test actually measures, why "sterile filtered" on a document is close…

122 questions
asked by ahmed_zerouali 19k · 2.0 years ago
38 votes 5 answers41k views
Is a 30G needle the right choice for drawing liraglutide at 1 mg/mL?

Concretely: a 30G needle · liraglutide · 1 mg/mL. I would like the axes of comparison first and the recommendation second. I have tried the first option and it works;…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by m_haraldsen 38k · 22 months ago
38 votes5 answers22k views
What gauge minimises coring through a rubber stopper?

My setup is a refrigerator with a logger and a small work area I wipe down, nothing more. These are treated as interchangeable and I do not think they are. If both…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
vial-inspection
vial-inspection

What you can learn by looking: cake morphology, meniscus films, fibres versus stopper fragments versus true particulates, clarity after…

66 questions
sterility
sterility

Sterility as a test result rather than an adjective. Covers what a sterility test actually measures, why "sterile filtered" on a document is close…

122 questions
asked by plunger_stop 18k · 2.3 years ago
37 votes 5 answers34k views
Is a 18G drawing needle the right choice for drawing orforglipron at 20 mg/mL?

Numbers first: an 18G drawing needle · orforglipron · 20 mg/mL. I want to know what the trade-off actually is rather than which option is fashionable. I would rather…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by b_delacroix 48k · 2.0 years ago
36 votes5 answers57k views
Is a 30G needle the right choice for drawing cagrilintide at 10 mg/mL?

Stated plainly: a 30G needle · cagrilintide · 10 mg/mL. Both of these get recommended confidently by different people, which suggests neither is obviously right. My…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by esther_vandeVelde 49k · 2.1 years ago
36 votes 5 answers31k views
Is a 30G needle the right choice for drawing a GLP-1 receptor agonist at 6.67 mg/mL?

What I am working with: a 30G needle · a GLP-1 receptor agonist · 6.67 mg/mL. Both of these get recommended confidently by different people, which suggests neither is…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by linnea_wahlberg 14k · 15 months ago
34 votes0 answers13k views
Is a 25G drawing needle the right choice for drawing a GLP-1 receptor agonist at 10 mg/mL?

What I am working with: a 25G drawing needle · a GLP-1 receptor agonist · 10 mg/mL. Both of these get recommended confidently by different people, which suggests…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by birk_nordahl 20k · 22 months ago
33 votes 5 answers35k views
Is a 25G drawing needle the right choice for drawing cagrilintide at 10 mg/mL?

What I am working with: a 25G drawing needle · cagrilintide · 10 mg/mL. I suspect the honest answer is that it depends, in which case I would like to know on what.…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by grainne_ahearn 13k · 13 months ago
33 votes5 answers20k views
Is a 18G drawing needle the right choice for drawing retatrutide at 20 mg/mL?

What I have: an 18G drawing needle · retatrutide · 20 mg/mL. I have used one of these for a while and I am considering switching, which requires a reason. What I care…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by eighty_six_hours 16k · 12 months ago
32 votes5 answers37k views
Is a 18G drawing needle the right choice for drawing retatrutide at 8 mg/mL?

Details up front: an 18G drawing needle · retatrutide · 8 mg/mL. I want to know what the trade-off actually is rather than which option is fashionable. I would rather…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by g_paskevicius 44k · 2.0 years ago
31 votes 5 answers33k views
Is a 30G needle the right choice for drawing tirzepatide at 10 mg/mL?

Conditions: a 30G needle · tirzepatide · 10 mg/mL. These are treated as interchangeable and I do not think they are. If both are acceptable I would like to know that,…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by s_bhattacharya 42k · 12 months ago
30 votes 3 answers35k views
How much product does syringe dead space actually cost me? Fixed-needle versus luer-lock, in µL and mg

I have been using 1 mL luer-lock syringes with detachable 27 G needles because that is what came in the box, and someone told me offhand that I am "wasting a third of…

dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
insulin-syringe
insulin-syringe

U-100 and U-40 insulin syringes as measuring instruments. A U-100 syringe is graduated in insulin units where 100 units equals 1 mL, so one unit…

268 questions
dosing-math
dosing-math

The arithmetic itself: milligrams to millilitres to insulin units, concentration after reconstitution, dose per draw, and vial-days per vial. Show…

811 questions
needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
asked by sample_id 17k · 22 months ago
30 votes5 answers35k views
Is a 30G needle the right choice for drawing oral semaglutide at 10 mg/mL?

Concretely: a 30G needle · oral semaglutide · 10 mg/mL. I would like the axes of comparison first and the recommendation second. I have tried the first option and it…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by sunniva_dahl 11k · 19 months ago
30 votes 5 answers28k views
How many times can I pierce a stopper with a 31G needle before coring?

This is the third vial from the same lot, so I can compare against two known-good ones. I can find plenty of assertions about this and almost no reasoning, which is…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
sterility
sterility

Sterility as a test result rather than an adjective. Covers what a sterility test actually measures, why "sterile filtered" on a document is close…

122 questions
vial-inspection
vial-inspection

What you can learn by looking: cake morphology, meniscus films, fibres versus stopper fragments versus true particulates, clarity after…

66 questions
sterile-water
sterile-water

Preservative-free sterile water for injection: appropriate for a single-withdrawal presentation, a poor choice for anything you intend to open…

14 questions
asked by petra_hovland 42k · 10 months ago
29 votes 5 answers38k views
Should I use a 27G needle to draw and something finer to administer?

I have photographs before and after reconstitution if the visual detail matters. This is a procedural question rather than a theoretical one, and I would like the…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
sterility
sterility

Sterility as a test result rather than an adjective. Covers what a sterility test actually measures, why "sterile filtered" on a document is close…

122 questions
asked by bridget_nyathi 16k · 14 months ago
28 votes5 answers39k views
Is a 31G needle the right choice for drawing ecnoglutide at 20 mg/mL?

For reference: a 31G needle · ecnoglutide · 20 mg/mL. The comparison I want does not seem to exist anywhere in a form I can evaluate. I have read the arguments for…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by area_percent 13k · 21 months ago
28 votes0 answers20k views
Is a 29G needle the right choice for drawing survodutide at 20 mg/mL?

The specifics, since they change the answer: a 29G needle · survodutide · 20 mg/mL. The comparison I want does not seem to exist anywhere in a form I can evaluate. I…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by dana_wexler 15k · 2.3 years ago
25 votes 5 answers39k views
Is a 25G drawing needle the right choice for drawing liraglutide at 10 mg/mL?

The case in front of me: a 25G drawing needle · liraglutide · 10 mg/mL. I would like the axes of comparison first and the recommendation second. I have tried the…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by ruaidhri_o_shea 51k · 19 months ago
25 votes 5 answers27k views
How many times can I pierce a stopper with a 27G needle before coring?

For context, I am working with a 10 mg presentation and a 2 mL fill. This is a procedural question rather than a theoretical one, and I would like the procedure…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
sterility
sterility

Sterility as a test result rather than an adjective. Covers what a sterility test actually measures, why "sterile filtered" on a document is close…

122 questions
vial-inspection
vial-inspection

What you can learn by looking: cake morphology, meniscus films, fibres versus stopper fragments versus true particulates, clarity after…

66 questions
asked by ellis_thorne 17k · 20 months ago
25 votes 5 answers21k views
Is a 30G needle the right choice for drawing tirzepatide at 6.67 mg/mL?

The case in front of me: a 30G needle · tirzepatide · 6.67 mg/mL. These are treated as interchangeable and I do not think they are. If both are acceptable I would…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by gel_pack_warm 13k · 9 months ago
24 votes5 answers14k views
Is a 29G needle the right choice for drawing retatrutide at 5 mg/mL?

Numbers first: a 29G needle · retatrutide · 5 mg/mL. I have used one of these for a while and I am considering switching, which requires a reason. What I care about…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by linnea_wahlberg 14k · 3 months ago
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