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Does a formic acid mobile phase change the purity number I get for mazdutide on a wide-pore C18 column?

Asked 23 Apr 2026Modified 3 months agoViewed 266 times
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Setup, so nobody has to ask: a formic acid mobile phase · mazdutide · a wide-pore C18 column.

The empirical answer seems settled. The explanation does not.

If the honest answer is that nobody knows, I would rather hear that than a plausible story.

Is the standard explanation correct, and if so, what is the evidence for it?

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askedmala_venkatesh21k2823 Apr 2026

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This question has not been answered. It has been viewed 266 times, which suggests the question is of interest and the answer is not obvious. If you can answer it with a source or a worked calculation, it will be read. See how to ask and answer.
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Ask PeptideStack is a static archive. Posting is closed, but the norms are worth stating: answer the question that was asked, show your working, cite the trial or the certificate, and say plainly where the evidence runs out.

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