I have vomited three times in the last ten days, always in the twenty-four to forty-eight hours after my injection, always in the morning, and each time I felt…
kidney-function
eGFR, creatinine, cystatin C and albuminuria: the acute haemodynamic dip that is not injury, the renal outcome data from the FLOW programme, and dehydration as a confounder.
Background: eight months on tirzepatide, uneventful until a bad fortnight of vomiting and diarrhoea after a dose increase, during which I ate very little and drank…
Details up front: albumin-to-creatinine ratio · sixteen weeks · tirzepatide. I have a result I cannot explain, and I would rather diagnose it than guess. I have…
I have been offered "a full panel" and I would rather understand what I am asking for than collect numbers I cannot interpret. My concern is specifically that active…
Stated plainly: LDL-C · triglycerides · semaglutide. Both of these get recommended confidently by different people, which suggests neither is obviously right. My…
Setup, so nobody has to ask: LDL-C · eight weeks · ecnoglutide. I noticed this today and I have not touched anything since, in case the state is diagnostic. I have…
The case in front of me: ferritin · ApoB · retatrutide. I would like the axes of comparison first and the recommendation second. I have tried the first option and it…
Stated plainly: ALT · AST · semaglutide. Both of these get recommended confidently by different people, which suggests neither is obviously right. My constraints are…
Stated plainly: lipase · potassium · survodutide. I suspect the honest answer is that it depends, in which case I would like to know on what. Assume I can obtain…
Details up front: TSH · magnesium · oral semaglutide. I want to know what the trade-off actually is rather than which option is fashionable. I would rather have a…
My eGFR is 92 and has been for years, which I had taken to mean my kidneys were not a topic. A urine albumin:creatinine ratio was added to a recent panel and came…
Numbers first: ApoB · sixteen weeks · oral semaglutide. I have a result I cannot explain, and I would rather diagnose it than guess. I have checked the obvious…
Numbers first: TSH · six weeks · oral semaglutide. Before I write this off, I want to check whether it is a known failure mode. I have the lot number, the certificate…
What I have: ApoB · sixteen weeks · tirzepatide. I have a result I cannot explain, and I would rather diagnose it than guess. I have checked the obvious explanations…
The specifics, since they change the answer: AST · ALT · a GLP-1 receptor agonist. The comparison I want does not seem to exist anywhere in a form I can evaluate. I…
The specifics, since they change the answer: AST · ten weeks · a GLP-1 receptor agonist. Something has gone wrong and I would like to know how badly before I decide…
I have been offered a "metabolic optimisation panel" by a private lab that runs to 58 analytes and costs about the same as a month of compounded semaglutide. My GP…
Male, 52, baseline creatinine 1.05 mg/dL with a reported eGFR of 85. Eight weeks into semaglutide, after two escalations, creatinine 1.18 mg/dL and eGFR 74. No…
Two data streams disagreeing, and I cannot reconcile them. Over eleven weeks my HbA1c fell from 7.1% to 6.4%. Over the same eleven weeks my sensor mean glucose was…
Stated plainly: lipase · two weeks · semaglutide. This is not behaving the way I expected and I want to understand the discrepancy before I act on it. I have…
The particulars: potassium · lipase · mazdutide. I am trying to choose between two options that are usually discussed as though only one exists. I am not optimising…
Concretely: GGT · albumin-to-creatinine ratio · orforglipron. I would like the axes of comparison first and the recommendation second. I have tried the first option…
Numbers first: eGFR · six weeks · tirzepatide. Before I write this off, I want to check whether it is a known failure mode. I have the lot number, the certificate and…
For reference: cystatin C · creatinine · a GLP-1 receptor agonist. I am trying to choose between two options that are usually discussed as though only one exists. I…
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