Accepted answer
It helps to be literal here: a plateau at four to six months is the expected shape of the curve, not a failure of it. Energy expenditure falls with mass, and the deficit closes itself unless intake falls further.
The first four weeks of loss is substantially fluid and glycogen. Each gram of stored glycogen carries roughly three grams of water, and total glycogen is on the order of 400 to 500 g, so the obligatory water shift alone accounts for a couple of kilograms. This is why the first month looks dramatic and the second looks like a plateau when in fact the fat-loss rate has not changed.
On the detail: cardio does not interfere with lean-mass retention at the volumes anyone here is doing; the interference effect in the literature appears at high concurrent volumes in trained athletes. What cardio does at a large deficit is add to the deficit, which is either the point or a problem depending on the objective.
The body-composition substudies in the major programmes consistently report that the proportion of weight lost as fat mass is approximately three quarters or better, with the lean-mass fraction falling within the range seen in dietary weight loss of comparable magnitude[1].
Train, eat the protein, measure something functional, and give the trend three months before you interpret it.
edited 19 Jun 2025 by jo_vandeberg — added the method parameters
5For what it is worth, my own result was within half a per cent of this. – ruaidhri_o_shea 5 months ago 4Any reason this would differ for a longer peptide? – kwn_analytical 3 months ago add a comment