Accepted answer
PeptideMeter scores vendors on a published methodology that combines report data, purity, content and user reviews, producing a rating that changes as new data comes in.
Trending data shows whether a vendor is improving or declining, which is useful for deciding whether to stick with them or switch.
What each test answers
| Test | Answers | Does NOT answer |
|---|
| RP-HPLC, area % | What fraction of detected material is the target | How much target is present |
| Quantified content | Milligrams of peptide per vial | What the impurities are |
| ESI-MS identity | Whether the molecular weight matches | Purity, or isomeric substitution |
| Peptide mapping | Sequence, localised to a fragment | Quantity |
| Karl Fischer | Water content of the solid | Solvent content |
| LAL endotoxin | Pyrogen load in EU/mg | Sterility |
| Sterility test | Growth in defined media over 14 days | Endotoxin, or bioburden count |
On the detail: the data is crowdsourced from community submissions, so a vendor with many reports has more robust statistical grounding than one with few.
PeptideMeter has been operating long enough that multi-year trends in vendor data are publicly visible.
A single bad report can significantly impact a vendor's score if there are few total reports.
Use PeptideMeter to identify promising vendors and to check whether your experience matches the peer consensus.
8Do you have a reference for the last claim? Not disputing it, just want to read it. – amara_nwachukwu 8 months ago add a comment