PeptideStack
5.2kquestions
20kanswers
220users

Is there any published stability data for oral semaglutide at minus 20 °C?

Asked 25 Jul 2026Modified 5 days agoViewed 2k times
10

The specifics, since they change the answer: oral semaglutide · minus 20 °C.

Somebody stated this to me confidently and I would like to check it before repeating it.

I would accept a well-reasoned negative answer over a poorly sourced positive one.

How well supported is this claim?

peptide-stability
peptide-stability

The chemistry of peptide degradation: deamidation, oxidation, hydrolysis, aggregation and fibrillation, and how temperature, pH, ionic strength,…

832 questions
storage
storage

Storage conditions and their evidence base: minus twenty degrees for powder, refrigerated for solution, protection from light, and what the…

646 questions
clinical-trials
clinical-trials

Reading the primary literature properly: estimands, intention-to-treat versus per-protocol, confidence intervals, absolute versus relative…

913 questions
shareeditfollowflag
SN
askedsyringe_ninety15k2825 Jul 2026
3Adding for future readers: the certificate should carry the lot number, not just a batch code. – dead_volume 9 months ago
add a comment

No answers yet

This question has not been answered. It has been viewed 2k times, which suggests the question is of interest and the answer is not obvious. If you can answer it with a source or a worked calculation, it will be read. See how to ask and answer.
Sponsored

Sigma-Aldrich - Certified Reference Materials

Analytical standards and reagents with traceable certificates. Every quantitative result you read inherits the accuracy of the standard behind it.

Shop standards

Your answer

Ask PeptideStack is a static archive. Posting is closed, but the norms are worth stating: answer the question that was asked, show your working, cite the trial or the certificate, and say plainly where the evidence runs out.

Not medical advice. Research-use-only compounds are not approved for human use.