Accepted answer
Start with the physical state. Lyophilised powder is stable at ambient for the duration of any normal lane; anything in solution is a different conversation entirely.
Tracking quality is the more informative signal: continuous scanning at every hop indicates a real logistics chain, and a tracking number that goes dark for a week indicates something else.
That is the argument for shipping lyophilised. A dry powder with low residual moisture is chemically stable at ambient for months; the degradation pathways that matter need water.
Phase-change pack hold times are a function of mass, latent heat and box insulation, and published figures for small parcels are on the order of a day or two.
Nothing here is medical advice, and research-use compounds are not approved for human use.
Judge the lane by tracking continuity rather than by days elapsed.