Page 15 of 35 · 832 questions tagged peptide-stability.
Stated plainly: dimerisation · a GLP-1 receptor agonist · minus 80 °C. I keep seeing this stated as a fact with no explanation attached, and unexplained facts make me…
The particulars: oral semaglutide · room temperature. I want a method I can write down and repeat, not a rule of thumb. I would rather over-engineer this than…
What I am working with: dulaglutide · eight weeks · 25 °C. I keep seeing this stated as a fact with no explanation attached, and unexplained facts make me suspicious.…
For reference: fibrillation · survodutide · 2–8 °C. I would like the mechanism, because I want to be able to reason about the cases nobody has written about. I have…
What I am working with: 37 °C · a GLP-1 receptor agonist. This is asserted often enough that I assumed it was established, and then I went looking for the source. I…
Details up front: racemisation · a C8 column. I suspect the usual explanation for this is wrong, or at least incomplete. I am aware this may have a boring answer. I…
Stated plainly: retatrutide · minus 80 °C. This is asserted often enough that I assumed it was established, and then I went looking for the source. I have searched…
Setup, so nobody has to ask: retatrutide · 3.33 mg/mL. I have worked this out and I would like someone to find the error, because I suspect there is one. My working…
Concretely: ecnoglutide · minus 80 °C · five days. I want to decide this in advance so that I am not deciding it under pressure later. Assume I will follow the plan I…
Details up front: racemisation · dulaglutide · minus 20 °C. I suspect the usual explanation for this is wrong, or at least incomplete. I am aware this may have a…
Conditions: survodutide · 8 mg/mL. I am trying to do this correctly the first time rather than learn it by getting it wrong. I have already made one mistake here that…
Details up front: mazdutide · six weeks · 25 °C. I can predict the outcome but I cannot explain it, which means I will get the next case wrong. I would like to know…
Setup, so nobody has to ask: retatrutide · two weeks · 4 °C. The empirical answer seems settled. The explanation does not. If the honest answer is that nobody knows,…
The case in front of me: ecnoglutide · 37 °C. I am trying to do this correctly the first time rather than learn it by getting it wrong. I have already made one…
Concretely: oxidation · 2–8 °C. This is one of those things that everyone repeats and nobody derives. This matters practically, not just academically, because it…
The particulars: liraglutide · three weeks · 25 °C. I understand the observation; what I do not understand is the mechanism behind it. I have read the two review…
Stated plainly: dulaglutide · minus 20 °C. Everything I have found on this is either a forum aside or a product page, neither of which I trust. I am comfortable with…
Setup, so nobody has to ask: room temperature · cagrilintide. This is asserted often enough that I assumed it was established, and then I went looking for the source.…
For reference: liraglutide · bacteriostatic water. I understand the observation; what I do not understand is the mechanism behind it. I have read the two review…
I have continuous temperature data for the period in question, which is unusual and I would like to use it. I would like the mechanism, because I want to be able to…
The case in front of me: semaglutide · 2–8 °C. The claim is plausible, which is exactly why I want to check it. I am able to read a paper if someone points me at one.…
Conditions: aspartimide formation · tirzepatide · 37 °C. This is one of those things that everyone repeats and nobody derives. This matters practically, not just…
The particulars: fibrillation · semaglutide · room temperature. I would like the mechanism, because I want to be able to reason about the cases nobody has written…
Concretely: oxidation · liraglutide · 25 °C. This is one of those things that everyone repeats and nobody derives. This matters practically, not just academically,…