Page 29 of 35 · 832 questions tagged peptide-stability.
What I am working with: dimerisation · 4 °C. The empirical answer seems settled. The explanation does not. If the honest answer is that nobody knows, I would rather…
Details up front: hydrolysis · dulaglutide · 40 °C. I can predict the outcome but I cannot explain it, which means I will get the next case wrong. I would like to…
Stated plainly: dulaglutide · two weeks · 40 °C. I am trying to build something sustainable rather than something thorough that I will abandon. I have already decided…
Stated plainly: aggregation · mazdutide · 25 °C. The empirical answer seems settled. The explanation does not. If the honest answer is that nobody knows, I would…
The particulars: tirzepatide · minus 20 °C. Somebody stated this to me confidently and I would like to check it before repeating it. I would accept a well-reasoned…
The case in front of me: ecnoglutide · four weeks · 25 °C. I want to know whether this is a real physical effect or an artefact of how it is measured. What prompted…
Concretely: semaglutide · 4 °C. I want to know whether there is evidence behind this or only repetition. I have checked the obvious registries and monographs without…
Conditions: semaglutide · 5 mg/mL. Please show the division. I want to check my own against yours. I would like the general form as well as the specific number, so I…
The case in front of me: aspartimide formation · tirzepatide · 25 °C. I want to know whether this is a real physical effect or an artefact of how it is measured. What…
What I have: hydrolysis · room temperature. I can predict the outcome but I cannot explain it, which means I will get the next case wrong. I would like to know how…
The case in front of me: survodutide · 2 mg/mL. I have done this once and I suspect I got away with it rather than got it right. For context: I keep records of every…
Concretely: aspartimide formation · 2–8 °C. I want to know whether this is a real physical effect or an artefact of how it is measured. What prompted the question is…
Concretely: semaglutide · 8 mg/mL. I want the working, not the result — I need to be able to redo it with different numbers. I care about the precision as well as the…
The specifics, since they change the answer: tirzepatide · ten weeks · 2–8 °C. I would like to define my thresholds before I have a result, for obvious reasons. I…
Concretely: aspartimide formation · minus 20 °C. I want to know whether this is a real physical effect or an artefact of how it is measured. What prompted the…
The case in front of me: oxidation · tirzepatide · minus 20 °C. I want to know whether this is a real physical effect or an artefact of how it is measured. What…
Numbers first: racemisation · retatrutide · 40 °C. I suspect the usual explanation for this is wrong, or at least incomplete. I am aware this may have a boring…
Concretely: semaglutide · twelve weeks · minus 80 °C. I want to decide this in advance so that I am not deciding it under pressure later. Assume I will follow the…
Numbers first: 30 °C · dulaglutide. I would rather be corrected now than propagate something wrong. I am specifically not interested in a testimonial; I am interested…
What I am working with: dulaglutide · 2–8 °C. This is asserted often enough that I assumed it was established, and then I went looking for the source. I have searched…
Setup, so nobody has to ask: dimerisation · 25 °C. The empirical answer seems settled. The explanation does not. If the honest answer is that nobody knows, I would…
What I am working with: dulaglutide · 5 mg/mL. This is a procedural question rather than a theoretical one, and I would like the procedure rather than the theory.…
Numbers first: a GLP-1 receptor agonist · 10 mg/mL. I can find plenty of assertions about this and almost no reasoning, which is usually a sign that nobody has…
The case in front of me: semaglutide · four weeks · 25 °C. I want to know whether this is a real physical effect or an artefact of how it is measured. What prompted…