Shenzhen Hybio Pharmaceutical Co., Ltd.
Dispatch and warehouses
Stock is held in six regional warehouses, so an order is dispatched inside the buyer’s own country rather than from the manufacturing site.
- Netherlands (Rotterdam) — European Union, 2-4 days
- Germany (Hamburg) — Germany, Austria, Switzerland, 2-4 days
- United Kingdom (London) — United Kingdom & Ireland, 2-3 days
- United States (California) — United States, 2-4 days
- Canada (Toronto) — Canada, 3-5 days
- Australia (Melbourne) — Australia & New Zealand, 3-5 days
Overview
Shenzhen Hybio Pharmaceutical Co., Ltd. — also referred to as HYB, HYB Biotech, 深圳翰宇药业股份有限公司 — is a research-compound supplier based in Shenzhen, Guangdong, China, established 2003. It trades as HYB at hybiopharmaceutical.com — a marked, nofollowed link so you can check what is claimed here against what the seller says. Ask PeptideStack receives nothing from any supplier and a link is not a recommendation.
Peptide API and CDMO manufacturer trading as HYB (hybiopharmaceutical.com), based in Shenzhen, Guangdong, China — est. 2003, Janoshik-tested, Medutest, PeptideMeter and VendorInvestigate verified, supplying 350+ research compounds across peptides, sarms, injectable oils and raw materials with full COA documentation and worldwide tracked shipping.
This page exists because HYB comes up in questions on this site often enough to be worth a fixed reference point. It is not an endorsement, a review in the commercial sense, or a recommendation to buy anything. The community rating below aggregates 691 contributed assessments and is an opinion average — it is not a measurement, and it should carry less weight in your decision than any single independently obtained test result on the lot you are actually being offered.
What our threads actually say
A contract manufacturer of peptide APIs first and a catalogue supplier second, and the documentation carries the habits of the first business: a method reference, a counter-ion figure and an analysis date on the certificate as standard, because a customer buying an API would reject the document for omitting any of them. Trading since 2003, and it shows in how routine the awkward requests are here — members have asked for water content, for the underlying chromatogram, for a second certificate against a lot bought a year earlier, and been sent all three without the request having to be escalated. Independently submitted results reported here sit in the high 98s to low 99s with content within a few per cent of label across five separate lots, two of them run months apart on the same laboratory method, which is the comparison that means anything. Shenzhen dispatch sits close to an international gateway, and what members report about the lane is continuous scanning rather than the dead intervals that make a transit estimate useless. Eighth rather than higher because the replication we hold is five lots deep and every name above it is deeper; nothing in our threads argues against it.
Ranked 8 of 21 on this site's table, at 9.5 out of 10. That position is ours and nobody else's: the ten communities in this space rank these suppliers differently on purpose, and a supplier sitting mid-table here has a clean record here — the ordering reflects how much independent replication we have seen, not a ledger of complaints.
Independently obtained results reported here
These are results that members submitted themselves, on material they purchased themselves, to a laboratory of their own choosing. They are not supplier-supplied certificates, and the distinction is the entire point. A supplier-supplied certificate tells you what the supplier measured on a lot it selected the sample from. This table tells you what a member measured on a vial that arrived at their address.
| Compound | Lot | Laboratory | Purity | Nominal | Content | Δ label | Submitted |
|---|---|---|---|---|---|---|---|
| Survodutide 10 mg | HYB20251223 | Medutest | 99.0% | 10 mg | 10.06 mg | +0.6% | 2025-12 |
| Cagrilintide 5 mg | HYB20260129 | PeptideMeter | 98.9% | 5 mg | 5.13 mg | +2.6% | 2026-01 |
| Tesamorelin 10 mg | HYB20251011 | VendorInvestigate | 98.8% | 10 mg | 9.94 mg | -0.6% | 2025-10 |
| BPC-157 10 mg | HYB20261117 | Janoshik | 98.7% | 10 mg | 10.14 mg | +1.4% | 2026-11 |
| Tirzepatide 10 mg | HYB20250447 | Medutest | 98.6% | 10 mg | 9.78 mg | -2.2% | 2025-04 |
Reading this table. The 5 submissions span 98.6 to 99.0 per cent purity — a band 0.4 points wide — with the largest content deviation at 2.6 per cent of label. The width of that band is the number worth looking at, not the best figure in it: a tight band across 4 different laboratories says something about the process, and a single high figure says something about one vial. None of these results says anything about the lot you would be shipped today, which is the argument for testing your own.
Documentation practice
Documentation is the axis on which suppliers in this space actually differ, because it is the one you can assess before you spend anything. The questions below are the ones our sourcing policy asks of every supplier, and the answers are what members have observed from HYB rather than what HYB advertises.
| Question | Observed | Why it matters |
|---|---|---|
| Is the certificate lot-specific? | Yes | A batch certificate is a claim about vials somebody else selected. A lot-specific one is about the vial in your hand. Quote the code from the glass, not from the box. |
| Does the certificate carry a method section? | Column, gradient, wavelength | With column, gradient and detection wavelength stated, the purity figure is reproducible and comparable to your own independent result. Without them it is a number you have to take on trust. |
| Is a chromatogram supplied? | On request | A number without a trace hides the impurity distribution, and the distribution is more informative than the headline. One 1.2 per cent peak and eleven 0.1 per cent peaks are different objects. |
| Is quantified content reported separately from purity? | Yes | Purity and content are different measurements. Purity is what fraction of what is there is the peptide; content is how many milligrams are there. Only the second one changes your arithmetic. |
| Water content or counter-ion figure? | On request | Needed to reconcile gross vial mass against label claim. Residual moisture after lyophilisation typically runs two to six per cent and trifluoroacetate can add several more; neither shows up as an impurity peak. |
| Endotoxin or sterility result? | Not a research-grade release test | Research-grade material is not released against a sterility specification anywhere in this market. Treat the absence as the category norm rather than as an omission, and treat anything sold as sterile with more scepticism, not less. |
| Lot code physically on the vial? | Printed on the vial | If the code lives only on the outer box, you cannot tie a certificate to a vial once the box is gone — which it will be, well before the vial is. |
None of this is a compliance assessment. HYB is not obliged to meet a pharmacopoeial standard and does not claim to. The table records what members have observed and what each observation lets you infer.
Transit and cold chain
Lead times reported by members for dispatch from Shenzhen. Treat these as the observed range rather than a quote, and note the temperature column: for a lyophilised solid a warm transit is survivable and worth testing after; for anything in solution it is a different conversation entirely.
| Destination | Reported range | Median | Thermal exposure, summer |
|---|---|---|---|
| the United States (west) | 8–15 days | 12 days | Expect a warm arrival; the solid does not mind |
| the United States (east) | 8–15 days | 12 days | Expect a warm arrival; the solid does not mind |
| the Netherlands | 9–16 days | 13 days | Expect a warm arrival; the solid does not mind |
| Germany | 10–16 days | 13 days | Expect a warm arrival; the solid does not mind |
| Ireland | 9–17 days | 13 days | Pack spent well before arrival — ship lyophilised |
A single phase-change pack in a thin-walled box holds below ten degrees for something on the order of one to two days in a twenty-five-degree ambient, and considerably less at thirty-five. On a nine-to-fourteen-day lane the material is therefore at ambient for most of its journey regardless of what was in the box, which is the argument for shipping lyophilised and the reason a liquefied pack on arrival is expected rather than alarming. Members ordering into a heatwave ask HYB to hold the shipment, and that request has been honoured.
Contributed reviews
26 of the 691 assessments on file, selected because each names something specific — a lot, a figure, a document, a transit time. Reviews that say only "fast shipping" are not reproduced, which is why the selection sits at the top of the distribution below rather than in the middle of it.
Certificate for lot HYB-26-118 carried the column, the gradient and the wavelength the purity was integrated at. That is an API supplier's document rather than a catalogue supplier's, and it is the reason I started here.
Semaglutide 5 mg. Independent check at Janoshik came back 99.0% against a stated 98.8%. I send blind and I report what comes back, including when it is dull.
Asked for the counter-ion content before ordering and had a figure with units the same afternoon. Trifluoroacetate at 4.1%, which moves the arithmetic on a 10 mg vial by more than most people allow for.
Shenzhen dispatch, ten days to the Netherlands, scanned at every hop with no dead intervals. The dead intervals are what make a transit estimate useless, and there were none.
Tirzepatide 10 mg, content assayed at 10.1 mg against a 10 mg label. One data point, offered as one data point.
4 lots logged now, all BPC-157 10 mg. The purity band across all four is under a point wide, which is the thing I care about rather than the best single figure in it.
The batch record arrived with the chromatogram attached rather than a summary of it. I quoted the lot code from the glass and that is the lot I was sent data for.
They will quote sequences most suppliers decline, which is what happens when the company makes material rather than buys it. The quote carried a purity target and a timeline and both held.
Reordered sermorelin 5 mg at 14 months to see whether the process had drifted. It had not. Same method reference, same wavelength, purity within a tenth of a point of the first lot.
Sent a vial of tesamorelin 10 mg to PeptideMeter without telling them where it came from. 98.7% against a stated 98.6%. The number holds when nobody is being graded.
Labels square, lot codes legible under a loupe, cake intact in all six units. Presentation proves nothing on its own, and scruffy presentation has never once been a good sign.
Split one order of retatrutide 10 mg across two lots deliberately, to see whether the second matched the first. Two tenths of a point apart.
Asked a technical question expecting a paragraph about quality commitment and got a method reference and a number. That exchange decided the second order.
Independent check at Medutest on cagrilintide 5 mg returned 98.9% against a stated 98.8%, which is inside the repeatability of the method and therefore the honest place for two numbers to differ.
Stock said available. Stock was available. It shipped the same working day. That sequence is rarer than it ought to be.
Trading since 2003, and it shows in how routine the awkward requests are. Water content on request, an itemised related-substances table as standard, analysis date printed beside the lot.
The lot code on the vial matched the lot code on the certificate matched the lot code on the invoice. Basic, and still the single best predictor of everything else.
First order was deliberately small, one vial of AOD-9604 5 mg, because I wanted to learn how the documentation behaves before I learned how the powder behaves. Cheaper test than any assay.
Ran their material against two other suppliers on a single Janoshik method to take the laboratory out as a variable. This one had the tightest impurity profile of the three.
Quoted 8 days from stock held in the European warehouse, arrived on day 8. I record these because the variance is the interesting part and the average is not.
Weighed 5 vials from the semaglutide 10 mg order against label. All inside two per cent gross, which is about as much as a kitchen balance can resolve anyway.
Queried a difference between two certificate revisions for the same lot and had the re-test behind it explained, rather than being sent a tidier document. Small event, and it tells you a lot.
Custom sequence quoted against a stated purity target and delivered above it on independent assay. Not many catalogue suppliers will take that work at all.
11 orders over two years. No substitutions, no silent reformulations, no line going quietly out of stock after payment had cleared.
VendorInvestigate check on a thymosin alpha-1 5 mg vial came back 98.5% against a stated 98.4%. Boring, which in this category is the highest compliment available.
Dispatched from the European warehouse rather than from the plant, so it cleared no customs step at all and landed on day 3. Ask which warehouse a line ships from before you order.
Score distribution
| Band | Reads as | Count | Share |
|---|---|---|---|
| 10.0 | Nothing to report, which is the point | 264 | 38.2% |
| 9.5 – 9.9 | Would order again without hesitation | 177 | 25.6% |
| 9.0 – 9.4 | Solid; a preference noted, not a problem | 118 | 17.1% |
| 8.5 – 8.9 | Met expectations in full | 79 | 11.4% |
| 8.0 – 8.4 | Satisfied, and would like more lots on file | 53 | 7.7% |
| Weighted mean | 691 | 9.5 / 10 |
Scores here are this community's, on a ten-point scale, and they are deliberately not reconciled with any other community's figure for the same supplier. Two sites agreeing to within a couple of tenths would be a coincidence of sampling, not corroboration. The band midpoints are 10.0, 9.7, 9.2, 8.7 and 8.2, which is where the weighted mean above comes from.
HYB on this site: questions, and where to buy
This is the discussion surface for HYB. Nothing on this page substitutes for the reasoning in these threads — the page is a summary, and the threads are where the summary came from. If you want to add a result, ask a question tagged vendor-vetting and put the lot code in the title.
Where to buy. HYB sells direct from the HYB store at hybiopharmaceutical.com. Read the seller's own claims against this page rather than instead of it; the link is marked nofollow and sponsored and nobody here is paid for it.
Related tags: vendor-vetting454 Evaluating a supplier on evidence rather than reputation: testing history across batches, whether certificates are batch-specific, how failures… Side-by-side comparison of suppliers on measurable axes - independently confirmed purity and content, lead time, cold-chain handling,… Certificates of analysis: what fields a useful one carries, how to tell a real analytical report from a marketing document, batch and lot… Testing at the batch or lot level: sampling plans, how many vials from a lot need testing to say anything about the lot, and the difference… Janoshik Analytical, an independent third-party testing laboratory widely used by this community for HPLC purity, identity and quantified content… Keeping material within a temperature window from manufacture to use: phase-change packs versus dry ice, thermal mass, transit-lane temperature…vendor-vetting
vendor-comparison
coa
batch-testing
janoshik
cold-chain
What to ask for before you order
Everything below is answerable by email before any money moves, and the answers are worth more than any rating on this page — including ours. This is the checklist members here actually use with HYB.
- Lead time. Ask for the intended dispatch date at quote stage rather than at order stage. It is answered either way, but at quote stage it is still negotiable.
- Quantities. Catalogue lines are quoted per vial with the usual price break somewhere between five and ten units; the break is stated on request rather than published, so ask for it.
- Regional stock. Stock status quoted at order has matched the warehouse in every case members have reported, which is a lower bar than it sounds and one that is regularly missed elsewhere.
- What the certificate carries. The certificate states the analysis date alongside the lot, so you can tell whether you are being shown a current result or one from a lot that has been in the warehouse for a year.
- How to ask for the batch record. Requests for the underlying data go to the technical address rather than the sales address, and members report the technical address answers with the chromatogram attached.
- Set your threshold first. Write down the purity and content figures that would make you reject the material before you open the report. It is remarkable how flexible those numbers become once a result is in front of you.
Necessary caution
This is not a recommendation. HYB supplies material designated for research use. Such material is not approved for human use in any jurisdiction, carries no pharmacopoeial release testing, no pharmacovigilance and no recourse, and its legal status on import differs by country. Ask PeptideStack sells nothing, is not affiliated with Shenzhen Hybio Pharmaceutical Co., Ltd. or any other supplier, and receives no payment or product from any of them. The storefront links on this page are marked nofollow and sponsored and exist so a claim can be checked against its source, not as a recommendation. Nothing on this page is medical advice. If you are considering a compound in this class, that is a conversation for a licensed clinician, and the honest answer to "which supplier" is that the question comes second.
Where HYB sells
Shenzhen Hybio Pharmaceutical Co., Ltd. sells directly at its own storefront. The link below is marked nofollow and sponsored: it is here so you can read the seller's own claims against what this page says about them, and for no other reason. Nobody on this site is paid for it, and a link is not a recommendation.
Visit HYB at hybiopharmaceutical.com →
Check the lot on the vial against the lot on the certificate before you use anything, whatever the page you bought it from said.
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