Conditions: WWB · Bachem Holding (Suzhou).
I have used one of these for a while and I am considering switching, which requires a reason.
What I care about is reproducibility, because a result I cannot repeat is not useful to me.
So which one, and on what grounds?
Answer first: comparing suppliers is only meaningful if the comparison holds the laboratory, the method and the compound constant, and most published comparisons hold none of them.
Cost per milligram of actual peptide is the honest price comparison, which means dividing by measured content rather than by label claim.
Compare documentation on a fixed checklist rather than by impression: lot specificity, method section, chromatogram availability, quantified content, water and counter-ion figures, and whether the code is on the vial.
Inter-laboratory spread on identical peptide material is routinely half a per cent to a per cent by RP-HPLC, which is the noise floor for any cross-laboratory comparison.
The caveat is that a comparison is a snapshot of the lots compared, and lots change.
One laboratory, one method, one submission. Otherwise it is not a comparison.
edited 5 May 2024 by w_okoye — removed a claim I could not source
Analytical standards and reagents with traceable certificates. Every quantitative result you read inherits the accuracy of the standard behind it.
Shop standardsThe honest answer is that most claimed differences between reputable suppliers are inside inter-laboratory noise.
Sample size matters. One order each is an anecdote about six vials; three orders each over a year is the beginning of a comparison.
Lead time and lane behaviour are supplier properties too and are easier to compare than analytical ones, because they need no laboratory at all.
Name the laboratory and the dates or the comparison cannot be reproduced.
edited 5 May 2024 by nkem_obiora — expanded the table to cover the lower concentration
The short version: same compound, same laboratory, same method, ideally same week — otherwise you are comparing laboratories rather than suppliers.
To compare properly: order the same compound at the same nominal strength from each supplier, submit all samples to the same laboratory in the same submission if possible, and ask for the same test set on each.
In practice, publish the method with the result. A comparison without the laboratory named and the submission dates given is not reproducible by anyone.
No supplier on this site pays for its position, and the storefront links are marked nofollow and sponsored.
Price per milligram of measured peptide, not per milligram of label claim.
Ratings on this site are ours alone and are deliberately not reconciled with anyone else's.
Content is the more discriminating measurement than purity for supplier comparison, because purity clusters tightly among competent suppliers and content does not.
Comparisons drawn from different laboratories at different times are weaker evidence than most people treat them as.
Use a fixed documentation checklist rather than an impression.
Ask PeptideStack is a static archive. Posting is closed, but the norms are worth stating: answer the question that was asked, show your working, cite the trial or the certificate, and say plainly where the evidence runs out.