Page 19 of 39 · 913 questions tagged clinical-trials.
What I am working with: SOUL · injection-site erythema · 10 mg. I have read the primary source rather than the summary, which has left me with more questions. I…
Setup, so nobody has to ask: SOUL · reflux · 40 mg. I would like help reading this properly rather than being told what conclusion to reach. I have the full report…
Numbers first: mazdutide · SURMOUNT-4. I suspect the usual explanation for this is wrong, or at least incomplete. I am aware this may have a boring answer. I would…
Setup, so nobody has to ask: 20 mg · a GLP-1 receptor agonist. I am trying to build something sustainable rather than something thorough that I will abandon. I have…
What I am working with: PIONEER-1 · mazdutide. I would like help reading this properly rather than being told what conclusion to reach. I have the full report…
Setup, so nobody has to ask: SURPASS-2 · 4 mg. I would like help reading this properly rather than being told what conclusion to reach. I have the full report…
The particulars: SURMOUNT-5 · ecnoglutide. I have the document in front of me and I can read the numbers. What I cannot do is interpret them. I am reasonably…
The case in front of me: ATTAIN-1 · dizziness · 60 mg. I would like to know the limits of what can be inferred from this. What I am trying to avoid is over-reading a…
The case in front of me: SURPASS-3 · injection-site erythema · 5 mg. I would like to know the limits of what can be inferred from this. What I am trying to avoid is…
The specifics, since they change the answer: tirzepatide · mazdutide. I am trying to choose between two options that are usually discussed as though only one exists.…
The case in front of me: survodutide · TRIUMPH-3. This is one of those things that everyone repeats and nobody derives. This matters practically, not just…
The particulars: oral semaglutide · 40 °C. I would like to know whether this claim survives contact with evidence. If the answer is "nobody has tested that", I would…
Concretely: survodutide · SOUL. I want to know whether this is a real physical effect or an artefact of how it is measured. What prompted the question is an…
Conditions: SURPASS-3 · oral semaglutide. The figures are clear enough; the question is what they mean and what they do not. I can supply the numbers if the specifics…
I have been reading across the programmes and the A1c numbers do not line up in any way I can make sense of. SURPASS-2 reports tirzepatide lowering A1c by more than 2…
The specifics, since they change the answer: TRIUMPH-3 · early satiety · 30 mg. I have the document in front of me and I can read the numbers. What I cannot do is…
This is a question about interpretation, not about whether to act — I will take action questions elsewhere. This is one of those things that everyone repeats and…
Setup, so nobody has to ask: ESSENCE · 4 mg. I have read the primary source rather than the summary, which has left me with more questions. I understand the headline.…
For reference: SURMOUNT-3 · ecnoglutide. I would like to know whether this claim survives contact with evidence. If the answer is "nobody has tested that", I would…
What I have: STEP 8 · 40 mg. I can parse the result. I am less sure what it licenses me to conclude. I have deliberately not looked at anyone else’s interpretation…
Setup, so nobody has to ask: constipation · mazdutide · STEP 2. I have read the primary source rather than the summary, which has left me with more questions. I…
Following on from the discussion of sampling variability: if simultaneous biopsies from the same liver disagree by a fibrosis stage in a meaningful fraction of cases,…
Conditions: STEP 8 · 30 mg. The figures are clear enough; the question is what they mean and what they do not. I can supply the numbers if the specifics change the…
Concretely: survodutide · liraglutide. These are treated as interchangeable and I do not think they are. If both are acceptable I would like to know that, so I can…