Page 31 of 39 · 913 questions tagged clinical-trials.
What I have: a GLP-1 receptor agonist · room temperature. I would rather be corrected now than propagate something wrong. I am specifically not interested in a…
The particulars: oral semaglutide · survodutide. I am trying to choose between two options that are usually discussed as though only one exists. I am not optimising…
What I have: REDEFINE-1 · hair thinning · 15 mg. I can parse the result. I am less sure what it licenses me to conclude. I have deliberately not looked at anyone…
The particulars: TRIUMPH-1 · 60 mg. I want to understand what this actually establishes, as opposed to what it is being used to imply. My concern is that I am being…
For reference: SURPASS-3 · 20 mg. I want to understand what this actually establishes, as opposed to what it is being used to imply. My concern is that I am being…
Setup, so nobody has to ask: dulaglutide · liraglutide. I suspect the honest answer is that it depends, in which case I would like to know on what. Assume I can…
Numbers first: PIONEER-1 · early satiety. I can parse the result. I am less sure what it licenses me to conclude. I have deliberately not looked at anyone else’s…
Numbers first: cagrilintide · survodutide. I have used one of these for a while and I am considering switching, which requires a reason. What I care about is…
The specifics, since they change the answer: TRIUMPH-3 · ecnoglutide. I would like to know whether this claim survives contact with evidence. If the answer is "nobody…
The specifics, since they change the answer: PIONEER-1 · ecnoglutide. I have the document in front of me and I can read the numbers. What I cannot do is interpret…
For reference: STEP 5 · nausea · 2 mg. I want to understand what this actually establishes, as opposed to what it is being used to imply. My concern is that I am…
Numbers first: 2 mg · orforglipron. I would rather over-plan the first cycle and simplify later. I am prepared to do the work if someone can tell me which work…
Numbers first: STEP 1 · 40 mg. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear to disagree, which…
The case in front of me: SURPASS-2 · tirzepatide. I would like to know the limits of what can be inferred from this. What I am trying to avoid is over-reading a…
Conditions: PIONEER-4 · reflux · 60 mg. I would like to know the limits of what can be inferred from this. What I am trying to avoid is over-reading a single result,…
Concretely: headache · liraglutide · REDEFINE-1. I would like to know the limits of what can be inferred from this. What I am trying to avoid is over-reading a single…
I have three data points across nine months, which I hope is enough to see a trend. I suspect the usual explanation for this is wrong, or at least incomplete. I am…
What I am working with: SUSTAIN-6 · reflux. I have read the primary source rather than the summary, which has left me with more questions. I understand the headline.…
For reference: PIONEER-1 · survodutide. I want to understand what this actually establishes, as opposed to what it is being used to imply. My concern is that I am…
The particulars: STEP 2 · semaglutide. I have the document in front of me and I can read the numbers. What I cannot do is interpret them. I am reasonably comfortable…
The specifics, since they change the answer: SOUL · constipation · 30 mg. I want to understand what this actually establishes, as opposed to what it is being used to…
Numbers first: SURMOUNT-3 · early satiety · 15 mg. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear…
For reference: SURPASS-3 · hair thinning. I want to understand what this actually establishes, as opposed to what it is being used to imply. My concern is that I am…
Conditions: survodutide · mazdutide. These are treated as interchangeable and I do not think they are. If both are acceptable I would like to know that, so I can stop…