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dead-space

Page 3 of 5 · 110 questions tagged dead-space.

110 questions · sorted by votes · page 3 of 5

20 votes5 answers18k views
What is the dead-space loss per draw with a 18G drawing needle at 2.5 mg/mL?

Details up front: an 18G drawing needle · 2.5 mg/mL. This should be a straightforward calculation and I keep getting two different answers. The numbers are arbitrary;…

dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
insulin-syringe
insulin-syringe

U-100 and U-40 insulin syringes as measuring instruments. A U-100 syringe is graduated in insulin units where 100 units equals 1 mL, so one unit…

268 questions
dosing-math
dosing-math

The arithmetic itself: milligrams to millilitres to insulin units, concentration after reconstitution, dose per draw, and vial-days per vial. Show…

811 questions
asked by nynke_dekker 18k · 18 months ago
20 votes 3 answers17k views
Air bubbles versus dead space — are they the same loss, and does back-loading or an air flush recover anything?

I have started to suspect I have been conflating two different problems. When I draw and see a bubble in the barrel, I tap it up and expel it and redraw. When I read…

dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
insulin-syringe
insulin-syringe

U-100 and U-40 insulin syringes as measuring instruments. A U-100 syringe is graduated in insulin units where 100 units equals 1 mL, so one unit…

268 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dosing-math
dosing-math

The arithmetic itself: milligrams to millilitres to insulin units, concentration after reconstitution, dose per draw, and vial-days per vial. Show…

811 questions
asked by rhian_prydderch 44k · 5 months ago
20 votes0 answers13k views
Is a 27G needle the right choice for drawing cagrilintide at 2.5 mg/mL?

What I am working with: a 27G needle · cagrilintide · 2.5 mg/mL. I suspect the honest answer is that it depends, in which case I would like to know on what. Assume I…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by tare_and_weigh 18k · 9 months ago
20 votes5 answers7.7k views
Is a 27G needle the right choice for drawing liraglutide at 6.67 mg/mL?

Concretely: a 27G needle · liraglutide · 6.67 mg/mL. These are treated as interchangeable and I do not think they are. If both are acceptable I would like to know…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by siobhan_deasy 16k · 12 months ago
20 votes 1 answer5.8k views
Is a 29G needle the right choice for drawing retatrutide at 3.33 mg/mL?

Numbers first: a 29G needle · retatrutide · 3.33 mg/mL. I have used one of these for a while and I am considering switching, which requires a reason. What I care…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by zainab_mustafa 16k · 39 days ago
20 votes 3 answers5.1k views
Is a 30G needle the right choice for drawing oral semaglutide at 1 mg/mL?

Conditions: a 30G needle · oral semaglutide · 1 mg/mL. These are treated as interchangeable and I do not think they are. If both are acceptable I would like to know…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by retest_please 13k · 2 months ago
19 votes 5 answers28k views
Is a 31G needle the right choice for drawing semaglutide at 3.33 mg/mL?

The particulars: a 31G needle · semaglutide · 3.33 mg/mL. I am trying to choose between two options that are usually discussed as though only one exists. I am not…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by tess_amankwah 48k · 2.1 years ago
19 votes 3 answers27k views
Why is comparing a 10 mg vial to a 4-dose pen apples-to-oranges, and how much does dead space really cost?

Someone told me a 10 mg vial and a carton of four 2.4 mg pens contain "basically the same amount of drug", which is 10 mg against 9.6 mg, so on the face of it that is…

cost-analysis
cost-analysis

Cost arithmetic done honestly: cost per milligram after dead-space loss, list versus net price, comparing a multi-dose vial to a fixed-dose pen,…

261 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
insulin-syringe
insulin-syringe

U-100 and U-40 insulin syringes as measuring instruments. A U-100 syringe is graduated in insulin units where 100 units equals 1 mL, so one unit…

268 questions
dosing-math
dosing-math

The arithmetic itself: milligrams to millilitres to insulin units, concentration after reconstitution, dose per draw, and vial-days per vial. Show…

811 questions
asked by tadhg_o_riordan 14k · 20 months ago
19 votes 5 answers24k views
Is a 25G drawing needle the right choice for drawing tirzepatide at 2.5 mg/mL?

Concretely: a 25G drawing needle · tirzepatide · 2.5 mg/mL. These are treated as interchangeable and I do not think they are. If both are acceptable I would like to…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by greta_holzmann 15k · 13 months ago
19 votes5 answers14k views
Is a 29G needle the right choice for drawing ecnoglutide at 20 mg/mL?

The specifics, since they change the answer: a 29G needle · ecnoglutide · 20 mg/mL. The comparison I want does not seem to exist anywhere in a form I can evaluate. I…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by klara_novotna 16k · 11 months ago
19 votes 5 answers9.1k views
Is a 31G needle the right choice for drawing retatrutide at 3.33 mg/mL?

Details up front: a 31G needle · retatrutide · 3.33 mg/mL. I have used one of these for a while and I am considering switching, which requires a reason. What I care…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
sterile-water
sterile-water

Preservative-free sterile water for injection: appropriate for a single-withdrawal presentation, a poor choice for anything you intend to open…

14 questions
asked by orla_sheridan 14k · 8 months ago
19 votes 5 answers5k views
Is a 18G drawing needle the right choice for drawing orforglipron at 8 mg/mL?

Details up front: an 18G drawing needle · orforglipron · 8 mg/mL. I have used one of these for a while and I am considering switching, which requires a reason. What I…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by lipid_panel_q 44k · 6 months ago
18 votes5 answers19k views
Is a 27G needle the right choice for drawing tirzepatide at 10 mg/mL?

Conditions: a 27G needle · tirzepatide · 10 mg/mL. These are treated as interchangeable and I do not think they are. If both are acceptable I would like to know that,…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by dermot_kiely 14k · 2.3 years ago
18 votes 5 answers8.3k views
Is a 18G drawing needle the right choice for drawing orforglipron at 2 mg/mL?

Numbers first: an 18G drawing needle · orforglipron · 2 mg/mL. I want to know what the trade-off actually is rather than which option is fashionable. I would rather…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by lukas_sedlacek 17k · 3 months ago
18 votes0 answers7.7k views
What is the dead-space loss per draw with a 18G drawing needle at 4 mg/mL?

Numbers first: an 18G drawing needle · 4 mg/mL. This should be a straightforward calculation and I keep getting two different answers. The numbers are arbitrary; the…

dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
insulin-syringe
insulin-syringe

U-100 and U-40 insulin syringes as measuring instruments. A U-100 syringe is graduated in insulin units where 100 units equals 1 mL, so one unit…

268 questions
dosing-math
dosing-math

The arithmetic itself: milligrams to millilitres to insulin units, concentration after reconstitution, dose per draw, and vial-days per vial. Show…

811 questions
asked by marta_szymanska 17k · 7 months ago
18 votes 3 answers6k views
Is a 29G needle the right choice for drawing dulaglutide at 3.33 mg/mL?

Numbers first: a 29G needle · dulaglutide · 3.33 mg/mL. I have used one of these for a while and I am considering switching, which requires a reason. What I care…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by syringe_ninety 15k · 9 months ago
18 votes 2 answers4.5k views
Is a 30G needle the right choice for drawing mazdutide at 4 mg/mL?

Stated plainly: a 30G needle · mazdutide · 4 mg/mL. Both of these get recommended confidently by different people, which suggests neither is obviously right. My…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by tess_amankwah 48k · 22 days ago
17 votes 5 answers35k views
Is a 29G needle the right choice for drawing ecnoglutide at 2 mg/mL?

The specifics, since they change the answer: a 29G needle · ecnoglutide · 2 mg/mL. I am trying to choose between two options that are usually discussed as though only…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by bufferline42 49k · 2.0 years ago
17 votes5 answers9.8k views
Is a 18G drawing needle the right choice for drawing ecnoglutide at 3.33 mg/mL?

The specifics, since they change the answer: an 18G drawing needle · ecnoglutide · 3.33 mg/mL. The comparison I want does not seem to exist anywhere in a form I can…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by pk_curve 12k · 11 months ago
17 votes 5 answers9.5k views
Is a 18G drawing needle the right choice for drawing ecnoglutide at 2 mg/mL?

For reference: an 18G drawing needle · ecnoglutide · 2 mg/mL. I am trying to choose between two options that are usually discussed as though only one exists. I am not…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by t_oyelaran 41k · 16 months ago
16 votes 5 answers21k views
Is a 29G needle the right choice for drawing semaglutide at 3.33 mg/mL?

For reference: a 29G needle · semaglutide · 3.33 mg/mL. The comparison I want does not seem to exist anywhere in a form I can evaluate. I have read the arguments for…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by sinead_gaffney 14k · 18 months ago
16 votes0 answers8.2k views
Is a 25G drawing needle the right choice for drawing tirzepatide at 4 mg/mL?

Conditions: a 25G drawing needle · tirzepatide · 4 mg/mL. I would like the axes of comparison first and the recommendation second. I have tried the first option and…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by helena_vidmar 18k · 10 months ago
16 votes 3 answers6.7k views
Is a 18G drawing needle the right choice for drawing ecnoglutide at 20 mg/mL?

For reference: an 18G drawing needle · ecnoglutide · 20 mg/mL. I am trying to choose between two options that are usually discussed as though only one exists. I am…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by rosa_mendieta 13k · 9 months ago
15 votes 5 answers34k views
Is a 25G drawing needle the right choice for drawing cagrilintide at 2.5 mg/mL?

Stated plainly: a 25G drawing needle · cagrilintide · 2.5 mg/mL. I suspect the honest answer is that it depends, in which case I would like to know on what. Assume I…

needle-gauge
needle-gauge

Gauge and length selection, the trade-off between draw time and tissue trauma, coring risk with larger-bore needles, and why a fixed-needle…

85 questions
injection-technique
injection-technique

Technique questions: angle, pinch versus flat, aspiration, injection speed, air bubbles, and the handling steps that determine whether you deliver…

90 questions
dead-space
dead-space

The volume trapped in the syringe hub and needle after the plunger bottoms out. It is small in absolute terms and large as a fraction of a small…

110 questions
asked by dana_wexler 15k · 2.3 years ago