Tiredness on treatment: how much is energy deficit, how much is dehydration or electrolyte drift, how much is genuinely drug-attributable, and what the placebo arms reported.
I am five months in, down 16 kg, and flattened. Not sleepy, exactly. More that everything costs more than it used to: stairs, conversations, training sessions I used…
Down 19 kg over seven months on semaglutide. My DEXA says I have lost 1.4 kg of lean soft tissue, which everyone tells me is a good result. But in the gym I am…
I have added a lot of cardio because it felt like the responsible thing to do and now I am not sure it is helping. Current week: three full-body lifting sessions,…
I have been offered "a full panel" and I would rather understand what I am asking for than collect numbers I cannot interpret. My concern is specifically that active…
Details up front: vomiting · 1,000 kcal. I have a result I cannot explain, and I would rather diagnose it than guess. I have checked the obvious explanations and…
The specifics, since they change the answer: fatigue · 1,200 kcal. Something has gone wrong and I would like to know how badly before I decide what to do. Nothing…
Setup, so nobody has to ask: hair thinning · 1,100 kcal. I noticed this today and I have not touched anything since, in case the state is diagnostic. I have not…
I would like to sanity-check the electrolyte question with numbers rather than by adding a supplement and seeing what happens. My hypothesis is that the reason people…
Scale weight, waist circumference and a repetition maximum, all logged weekly. I would like to know the limits of what can be inferred from this. What I am trying to…
Stated plainly: nausea · 1,100 kcal. I noticed this today and I have not touched anything since, in case the state is diagnostic. I have not discarded anything yet,…
Concretely: headache · 1,400 kcal. I think I have a problem. I am not yet sure whether it is a real problem or a measurement artefact. I want to know whether this is…
Stated plainly: headache · 1,100 kcal. I noticed this today and I have not touched anything since, in case the state is diagnostic. I have not discarded anything yet,…
Numbers first: reflux · 1,200 kcal. I have a result I cannot explain, and I would rather diagnose it than guess. I have checked the obvious explanations and…
Conditions: constipation · 900 kcal. I think I have a problem. I am not yet sure whether it is a real problem or a measurement artefact. I want to know whether this…
Setup, so nobody has to ask: constipation · 1,400 kcal. I noticed this today and I have not touched anything since, in case the state is diagnostic. I have not…
Setup, so nobody has to ask: early satiety · 1,400 kcal. I noticed this today and I have not touched anything since, in case the state is diagnostic. I have not…
Numbers first: fatigue · 800 kcal. Before I write this off, I want to check whether it is a known failure mode. I have the lot number, the certificate and the date,…
For reference: reflux · 800 kcal. Something has gone wrong and I would like to know how badly before I decide what to do. Nothing else in the setup changed, which is…
What I have: injection-site erythema · 1,000 kcal. I have a result I cannot explain, and I would rather diagnose it than guess. I have checked the obvious…
Setup, so nobody has to ask: constipation · 1,100 kcal. This is not behaving the way I expected and I want to understand the discrepancy before I act on it. I have…
Stated plainly: headache · 900 kcal. I noticed this today and I have not touched anything since, in case the state is diagnostic. I have not discarded anything yet,…
Concretely: nausea · 900 kcal. I have two candidate explanations and no way to distinguish them. The same procedure has worked without incident several times…
Concretely: early satiety · 1,100 kcal. I have two candidate explanations and no way to distinguish them. The same procedure has worked without incident several times…
For reference: reflux · 1,000 kcal. An unexpected observation, and I would like a differential rather than reassurance. The conditions were within what I understood…
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