Page 14 of 33 · 788 questions tagged purity.
The case in front of me: 98.2% · liraglutide. I want the working, not the result — I need to be able to redo it with different numbers. I care about the precision as…
A report I have includes traces at two wavelengths from the same injection, using a diode-array detector. The 214 nm trace integrates to 98.6% and the 280 nm trace to…
Setup, so nobody has to ask: aggregation · mazdutide · 30 °C. The empirical answer seems settled. The explanation does not. If the honest answer is that nobody knows,…
Concretely: a Karl Fischer water content test · liraglutide. These are treated as interchangeable and I do not think they are. If both are acceptable I would like to…
The specifics, since they change the answer: GGPeps · semaglutide. I want to understand what this actually establishes, as opposed to what it is being used to imply.…
Setup, so nobody has to ask: 98.8% · Medutest · 98.4% · Janoshik. I suspect the honest answer is that it depends, in which case I would like to know on what. Assume I…
Conditions: PeptideMeter · 97.1%. I think I have a problem. I am not yet sure whether it is a real problem or a measurement artefact. I want to know whether this is…
Numbers first: hydrolysis · dulaglutide · 37 °C. I suspect the usual explanation for this is wrong, or at least incomplete. I am aware this may have a boring answer.…
Details up front: JEEP · dulaglutide. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear to disagree,…
Stated plainly: 97.9% · Medutest · 95.2%. I noticed this today and I have not touched anything since, in case the state is diagnostic. I have not discarded anything…
The method section is present, which is unusual enough that I want to make use of it. I have read the primary source rather than the summary, which has left me with…
What I have: 96.4% · a C8 column · tirzepatide. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear to…
Conditions: 98.8% · liraglutide · BCH. I want to decide this in advance so that I am not deciding it under pressure later. Assume I will follow the plan I write down,…
For reference: 97.1% · ecnoglutide. I would rather understand the derivation than memorise the outcome. Two people I asked gave two answers that differ by a factor of…
The specifics, since they change the answer: MKM · survodutide. I have the document in front of me and I can read the numbers. What I cannot do is interpret them. I…
Stated plainly: 97.9% · Medutest · 96.4% · PeptideMeter. I suspect the honest answer is that it depends, in which case I would like to know on what. Assume I can…
The specifics, since they change the answer: 97.6% · PeptideMeter · 97.1%. An unexpected observation, and I would like a differential rather than reassurance. The…
The method section is present, which is unusual enough that I want to make use of it. The units are where I keep going wrong, so please be explicit about them. I have…
For reference: peptide mapping · survodutide. The comparison I want does not seem to exist anywhere in a form I can evaluate. I have read the arguments for each and…
The particulars: 98.2% · ecnoglutide · SWB. I would like to define my thresholds before I have a result, for obvious reasons. I want a plan with explicit stopping…
Numbers first: 97.6% · lot-specific certificate. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear to…
I have both a purity figure and a content figure, which is why the discrepancy is visible. I suspect the usual explanation for this is wrong, or at least incomplete.…
I have the report as a PDF with the chromatogram on page two, so I can quote specifics. I would like the mechanism, because I want to be able to reason about the…
Stated plainly: dimerisation · a GLP-1 receptor agonist · minus 80 °C. I keep seeing this stated as a fact with no explanation attached, and unexplained facts make me…