Page 13 of 39 · 913 questions tagged clinical-trials.
Concretely: STEP 3 · tirzepatide. I want to know whether there is evidence behind this or only repetition. I have checked the obvious registries and monographs…
I have the full paper rather than the abstract, and the supplementary appendix. I can do the algebra. I am not confident about the conversion factors. If there is a…
The case in front of me: hair thinning · tirzepatide · FLOW. The figures are clear enough; the question is what they mean and what they do not. I can supply the…
Concretely: SELECT · fatigue. The figures are clear enough; the question is what they mean and what they do not. I can supply the numbers if the specifics change the…
What I have: SUSTAIN-6 · dulaglutide. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear to disagree,…
What I am working with: ten weeks · a GLP-1 receptor agonist. This has the shape of a fact but I cannot find its origin. What I found instead were three secondary…
The case in front of me: hair thinning · tirzepatide · STEP 3. I would like to know the limits of what can be inferred from this. What I am trying to avoid is…
The case in front of me: SURMOUNT-2 · fatigue. I would like to know the limits of what can be inferred from this. What I am trying to avoid is over-reading a single…
Concretely: early satiety · oral semaglutide · SURMOUNT-2. The figures are clear enough; the question is what they mean and what they do not. I can supply the numbers…
I am asking about the protocol logic rather than about my own case specifically. I want to understand what this actually establishes, as opposed to what it is being…
What I have: injection-site erythema · retatrutide · PIONEER-4. I can parse the result. I am less sure what it licenses me to conclude. I have deliberately not looked…
Setup, so nobody has to ask: STEP 2 · dizziness. I would like help reading this properly rather than being told what conclusion to reach. I have the full report…
The particulars: oral semaglutide · SELECT. I would like the mechanism, because I want to be able to reason about the cases nobody has written about. I have tried to…
The particulars: SUSTAIN-6 · semaglutide. I want to understand what this actually establishes, as opposed to what it is being used to imply. My concern is that I am…
Concretely: SELECT · liraglutide. The claim is plausible, which is exactly why I want to check it. I am able to read a paper if someone points me at one. Can anyone…
The specifics, since they change the answer: TRIUMPH-1 · survodutide. Somebody stated this to me confidently and I would like to check it before repeating it. I would…
What I am working with: FLOW · injection-site erythema · 10 mg. I have read the primary source rather than the summary, which has left me with more questions. I…
The specifics, since they change the answer: PIONEER-4 · headache · 2 mg. I have the document in front of me and I can read the numbers. What I cannot do is interpret…
For reference: FLOW · semaglutide. I want to understand what this actually establishes, as opposed to what it is being used to imply. My concern is that I am being…
The specifics, since they change the answer: oral semaglutide · mazdutide. I am trying to choose between two options that are usually discussed as though only one…
Conditions: STEP 4 · fatigue · 5 mg. The figures are clear enough; the question is what they mean and what they do not. I can supply the numbers if the specifics…
What I have: SURMOUNT-5 · 40 mg. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear to disagree, which…
Every trial in metabolic dysfunction-associated steatohepatitis reports two co-primary endpoints with oddly constructed names: "resolution of steatohepatitis without…
The case in front of me: ecnoglutide · 37 °C. I want to know whether there is evidence behind this or only repetition. I have checked the obvious registries and…