Page 12 of 39 · 913 questions tagged clinical-trials.
What I am working with: constipation · mazdutide · REDEFINE-1. I would like help reading this properly rather than being told what conclusion to reach. I have the…
Concretely: TRIUMPH-1 · fatigue. The figures are clear enough; the question is what they mean and what they do not. I can supply the numbers if the specifics change…
I have the full paper rather than the abstract, and the supplementary appendix. I would rather understand the derivation than memorise the outcome. Two people I asked…
I have the full paper rather than the abstract, and the supplementary appendix. I can predict the outcome but I cannot explain it, which means I will get the next…
The label maximum gets treated as a destination — the "full dose", as though anything below it is partial. But a label maximum is the highest dose a sponsor took…
What I have: vomiting · orforglipron · STEP 1. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear to…
Stated plainly: TRIUMPH-3 · mazdutide. I have read the primary source rather than the summary, which has left me with more questions. I understand the headline. I do…
What I am working with: SURMOUNT-1 · dizziness. I have read the primary source rather than the summary, which has left me with more questions. I understand the…
What I am working with: FLOW · reflux. I have read the primary source rather than the summary, which has left me with more questions. I understand the headline. I do…
The particulars: injection-site erythema · semaglutide · STEP 5. I have the document in front of me and I can read the numbers. What I cannot do is interpret them. I…
The case in front of me: semaglutide · minus 20 °C. The claim is plausible, which is exactly why I want to check it. I am able to read a paper if someone points me at…
Numbers first: REDEFINE-1 · retatrutide. I can parse the result. I am less sure what it licenses me to conclude. I have deliberately not looked at anyone else’s…
My laboratory results are from the same laboratory each time, drawn fasting, which I gather matters. This is one of those things that everyone repeats and nobody…
The particulars: STEP 5 · nausea. I have the document in front of me and I can read the numbers. What I cannot do is interpret them. I am reasonably comfortable with…
What I have: ATTAIN-1 · hair thinning · 50 mg. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear to…
For reference: SURPASS-3 · early satiety · 8 mg. I have the document in front of me and I can read the numbers. What I cannot do is interpret them. I am reasonably…
For reference: FLOW · survodutide. I want to understand what this actually establishes, as opposed to what it is being used to imply. My concern is that I am being…
I have been trying to build a spreadsheet of published weight-loss results so I can compare programmes properly, and I keep tripping over the same thing. The primary…
What I am working with: retatrutide · STEP 4. I keep seeing this stated as a fact with no explanation attached, and unexplained facts make me suspicious. My…
Conditions: semaglutide · survodutide. These are treated as interchangeable and I do not think they are. If both are acceptable I would like to know that, so I can…
Setup, so nobody has to ask: STEP 1 · 50 mg. I have read the primary source rather than the summary, which has left me with more questions. I understand the headline.…
Numbers first: a GLP-1 receptor agonist · semaglutide. I want to know what the trade-off actually is rather than which option is fashionable. I would rather have a…
Conditions: SELECT · tirzepatide. The claim is plausible, which is exactly why I want to check it. I am able to read a paper if someone points me at one. Is there…
The case in front of me: semaglutide · cagrilintide. These are treated as interchangeable and I do not think they are. If both are acceptable I would like to know…