Page 34 of 39 · 913 questions tagged clinical-trials.
The particulars: ESSENCE · early satiety. I have the document in front of me and I can read the numbers. What I cannot do is interpret them. I am reasonably…
The particulars: liraglutide · PIONEER-4. I understand the observation; what I do not understand is the mechanism behind it. I have read the two review articles that…
I would like to know how much of this is established and how much is a reasonable story. I want to know what the trade-off actually is rather than which option is…
The case in front of me: ESSENCE · oral semaglutide. The claim is plausible, which is exactly why I want to check it. I am able to read a paper if someone points me…
Details up front: STEP 2 · dulaglutide. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear to…
The case in front of me: survodutide · REDEFINE-1. This is one of those things that everyone repeats and nobody derives. This matters practically, not just…
What I have: ESSENCE · hair thinning · 4 mg. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear to…
The case in front of me: SURMOUNT-5 · dizziness · 60 mg. I would like to know the limits of what can be inferred from this. What I am trying to avoid is over-reading…
Details up front: STEP 3 · 10 mg. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear to disagree,…
The particulars: TRIUMPH-3 · survodutide. I have the document in front of me and I can read the numbers. What I cannot do is interpret them. I am reasonably…
I have three data points across nine months, which I hope is enough to see a trend. I would like the arithmetic checked rather than the conclusion asserted. I have…
The particulars: tirzepatide · ESSENCE. I understand the observation; what I do not understand is the mechanism behind it. I have read the two review articles that…
Conditions: SURMOUNT-3 · liraglutide. The figures are clear enough; the question is what they mean and what they do not. I can supply the numbers if the specifics…
The specifics, since they change the answer: tirzepatide · 2–8 °C. I would like to know whether this claim survives contact with evidence. If the answer is "nobody…
The particulars: SUSTAIN-6 · early satiety. I have the document in front of me and I can read the numbers. What I cannot do is interpret them. I am reasonably…
Details up front: SURMOUNT-1 · retatrutide. I can parse the result. I am less sure what it licenses me to conclude. I have deliberately not looked at anyone else’s…
My laboratory results are from the same laboratory each time, drawn fasting, which I gather matters. The empirical answer seems settled. The explanation does not. If…
The case in front of me: ecnoglutide · tirzepatide. I would like the axes of comparison first and the recommendation second. I have tried the first option and it…
What I am working with: SELECT · dizziness · 10 mg. I have read the primary source rather than the summary, which has left me with more questions. I understand the…
Setup, so nobody has to ask: REDEFINE-1 · cagrilintide. This is asserted often enough that I assumed it was established, and then I went looking for the source. I…
Stated plainly: SURMOUNT-5 · reflux · 10 mg. I would like help reading this properly rather than being told what conclusion to reach. I have the full report including…
Setup, so nobody has to ask: SURMOUNT-5 · reflux. I would like help reading this properly rather than being told what conclusion to reach. I have the full report…
Numbers first: ESSENCE · 40 mg. I can parse the result. I am less sure what it licenses me to conclude. I have deliberately not looked at anyone else’s interpretation…
The case in front of me: TRIUMPH-3 · fatigue · 5 mg. The figures are clear enough; the question is what they mean and what they do not. I can supply the numbers if…