ivo_paunovic
Statistics background. I read confidence intervals before headlines.
15kreputation
30answers
3accepted
32questions
0·1·8badges g·s·b
58tags
40Food noise came back at month seven. Is that tolerance, and does it mean the dose has to go up?3 answers · 15k views · food-noise, dose-escalation, plateau38How do I get 20 units out of a vial reconstituted to 3.33 mg/mL without guessing?5 answers, accepted · 50k views · insulin-syringe, dosing-math, diluent-volume37How does semaglutide behave on a C4 column compared to mazdutide?5 answers, accepted · 14k views · hplc, purity, reference-standard34What does 98.8% purity on a C4 column actually tell me about a dulaglutide vial?0 answers · 32k views · hplc, purity, coa33Is survodutide at 8 mg/mL stable enough for ten weeks of multi-withdrawal use?2 answers · 21k views · peptide-stability, bacteriostatic-water, shelf-life31Is early satiety on a GLP-1 receptor agonist dose-dependent or dose-rate dependent?0 answers · 23k views · nausea, titration, gi-side-effects30What is the reported incidence of reflux on orforglipron in STEP 3?5 answers, accepted · 55k views · gi-side-effects, clinical-trials, nausea29How does QST compare to Shanghai Wibson Biotechnology on documentation quality?0 answers · 32k views · vendor-comparison, coa, vendor-vetting29How long does a Qingdao to Ireland lane usually take with tracking?5 answers, accepted · 38k views · international-shipping, customs, cold-chain28Does aspartimide formation produce a resolvable peak on a C4 column, or does it co-elute?5 answers, accepted · 28k views · hplc, purity, peptide-stability26Has anyone independently verified a Homopeptide tirzepatide batch COA?5 answers, accepted · 14k views · vendor-vetting, coa, batch-testing24Is 10 mg in 2.5 mL of 0.9% sodium chloride a sensible presentation for cagrilintide?5 answers, accepted · 12k views · diluent-volume, reconstitution, dosing-math23How do I tell constipation from an energy deficit on 1,400 kcal a day?5 answers, accepted · 26k views · fatigue, nutrition, electrolytes23How does the reference standard error propagate into my content figure?0 answers · 19k views · reference-standard, content-assay, purity23If I reconstitute a 40 mg vial with 2.5 mL of 0.9% sodium chloride, what concentration do I end up with?5 answers, accepted · 30k views · reconstitution, diluent-volume, dosing-math23What is the thermal exposure on a Zhuhai to New Zealand lane in summer?5 answers, accepted · 36k views · cold-chain, international-shipping, storage22Can I reconstitute cagrilintide at 10 mg/mL and still measure a small dose accurately?5 answers · 29k views · diluent-volume, insulin-syringe, dosing-math22What does a 1 Da mass shift on an ESI-MS spectrum indicate?5 answers, accepted · 4.5k views · mass-spec, purity, peptide-mapping21Is 95.2% a realistic purity ceiling for ecnoglutide given its chain length?5 answers · 3.5k views · purity, hplc, peptide-mapping20Is 2.5 mg/mL a sensible working concentration for liraglutide, or should I go lower?4 answers · 44k views · diluent-volume, reconstitution, dosing-math19How much protein in grams do I need at 81 kg on 900 kcal a day?5 answers, accepted · 12k views · protein-intake, nutrition, lean-mass18How many vial-days does a 60 mg vial give at 8 mg/mL on a weekly schedule?5 answers, accepted · 24k views · dosing-math, cost-analysis, diluent-volume18What is the real-world lead time from Xi’an to Singapore in winter?3 answers, accepted · 23k views · international-shipping, cold-chain, customs18What is the reported incidence of nausea on liraglutide in SOUL?5 answers · 10k views · gi-side-effects, clinical-trials, nausea15If I reconstitute a 30 mg vial with 3 mL of sterile water for injection, what concentration do I end up with?3 answers, accepted · 6k views · reconstitution, diluent-volume, dosing-math13Is lipase worth drawing at baseline before starting cagrilintide?5 answers, accepted · 8.5k views · bloodwork, harm-reduction, a1c11Is minus 20 °C an acceptable storage condition for lyophilised liraglutide?0 answers · 6.5k views · storage, peptide-stability, shelf-life11Would you accept 96.4% on oral semaglutide from QSC without a content assay?4 answers, accepted · 19k views · purity, content-assay, vendor-vetting6What does the mechanism of survodutide predict that REDEFINE-1 did not test?3 answers, accepted · 5.5k views · glp1-mechanism, clinical-trials, gip-receptor5Does HJ issue lot-specific documentation, or a batch certificate?5 answers, accepted · 17k views · batch-testing, coa, vendor-vetting5Does splitting a 20 mg weekly dose of a GLP-1 receptor agonist across two administrations change anything?0 answers · 8.2k views · split-dosing, dosing-math, glp1-mechanism1How does CPC compare to Guangzhou JEEP Biotechnology on documentation quality?3 answers · 1.7k views · vendor-comparison, coa, vendor-vetting