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Is SOUL a fair comparison of a GLP-1 receptor agonist against its comparator arm?

Asked 22 Aug 2025Modified 11 months agoViewed 7.5k times
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What I am working with: SOUL · a GLP-1 receptor agonist.

This is asserted often enough that I assumed it was established, and then I went looking for the source.

I have searched the primary literature and found one paper that is adjacent but not on point.

Has anyone verified this independently?

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askedbea_forsberg14k2822 Aug 2025

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This question has not been answered. It has been viewed 7.5k times, which suggests the question is of interest and the answer is not obvious. If you can answer it with a source or a worked calculation, it will be read. See how to ask and answer.
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