Page 23 of 39 · 913 questions tagged clinical-trials.
Conditions: ecnoglutide · retatrutide. I would like the axes of comparison first and the recommendation second. I have tried the first option and it works; the…
For reference: SOUL · 60 mg. I have the document in front of me and I can read the numbers. What I cannot do is interpret them. I am reasonably comfortable with…
What I am working with: SURMOUNT-1 · cagrilintide. I have read the primary source rather than the summary, which has left me with more questions. I understand the…
The case in front of me: STEP 1 · liraglutide. The figures are clear enough; the question is what they mean and what they do not. I can supply the numbers if the…
Numbers first: cagrilintide · STEP 1. I suspect the usual explanation for this is wrong, or at least incomplete. I am aware this may have a boring answer. I would…
I have the full paper rather than the abstract, and the supplementary appendix. I am at the decision point and I would rather think it through than improvise. I would…
The case in front of me: STEP 5 · oral semaglutide. I would like to know the limits of what can be inferred from this. What I am trying to avoid is over-reading a…
I have been on a stable schedule for eleven weeks, so this is not a first-week question. I have the document in front of me and I can read the numbers. What I cannot…
The specifics, since they change the answer: SURMOUNT-4 · semaglutide. I have the document in front of me and I can read the numbers. What I cannot do is interpret…
What I have: mazdutide · SURPASS-2. I can predict the outcome but I cannot explain it, which means I will get the next case wrong. I would like to know how confident…
What I am working with: dulaglutide · SURMOUNT-1. The empirical answer seems settled. The explanation does not. If the honest answer is that nobody knows, I would…
Stated plainly: dulaglutide · SURMOUNT-4. The empirical answer seems settled. The explanation does not. If the honest answer is that nobody knows, I would rather hear…
Stated plainly: SURMOUNT-5 · a GLP-1 receptor agonist. I have read the primary source rather than the summary, which has left me with more questions. I understand the…
SOUL tested oral semaglutide 14 mg daily in people with type 2 diabetes and either atherosclerotic cardiovascular disease or chronic kidney disease, and reported a…
What I am working with: SURMOUNT-OSA · 50 mg. I would like help reading this properly rather than being told what conclusion to reach. I have the full report…
Numbers first: cagrilintide · 4 °C. I am asking for verification rather than opinion, ideally with something I can read myself. It is possible the evidence exists and…
Concretely: ecnoglutide · STEP 8. I want to know whether this is a real physical effect or an artefact of how it is measured. What prompted the question is an…
The specifics, since they change the answer: liraglutide · REDEFINE-1. I understand the observation; what I do not understand is the mechanism behind it. I have read…
The specifics, since they change the answer: SURMOUNT-OSA · semaglutide. I would like to know whether this claim survives contact with evidence. If the answer is…
For reference: 15 mg · survodutide. I would like to define my thresholds before I have a result, for obvious reasons. I want a plan with explicit stopping rules, not…
I am reading the trial table rather than the press release, which is why the numbers differ. I would like the arithmetic checked rather than the conclusion asserted.…
What I am working with: dulaglutide · ESSENCE. The empirical answer seems settled. The explanation does not. If the honest answer is that nobody knows, I would rather…
What I have: PIONEER-1 · dulaglutide. I can parse the result. I am less sure what it licenses me to conclude. I have deliberately not looked at anyone else’s…
Details up front: FLOW · retatrutide. I can parse the result. I am less sure what it licenses me to conclude. I have deliberately not looked at anyone else’s…