Page 28 of 39 · 913 questions tagged clinical-trials.
Numbers first: a GLP-1 receptor agonist · PIONEER-1. I suspect the usual explanation for this is wrong, or at least incomplete. I am aware this may have a boring…
Conditions: semaglutide · mazdutide. These are treated as interchangeable and I do not think they are. If both are acceptable I would like to know that, so I can stop…
Setup, so nobody has to ask: SURMOUNT-2 · a GLP-1 receptor agonist. I would like help reading this properly rather than being told what conclusion to reach. I have…
Details up front: a GLP-1 receptor agonist · survodutide. I have used one of these for a while and I am considering switching, which requires a reason. What I care…
What I am working with: SOUL · dizziness. I would like help reading this properly rather than being told what conclusion to reach. I have the full report including…
Setup, so nobody has to ask: hair thinning · mazdutide · STEP 2. I would like help reading this properly rather than being told what conclusion to reach. I have the…
What I have: TRIUMPH-1 · constipation. I can parse the result. I am less sure what it licenses me to conclude. I have deliberately not looked at anyone else’s…
I have the full paper rather than the abstract, and the supplementary appendix. I suspect the usual explanation for this is wrong, or at least incomplete. I am aware…
What I am working with: SURMOUNT-5 · fatigue · 2.5 mg. I have read the primary source rather than the summary, which has left me with more questions. I understand the…
Concretely: TRIUMPH-3 · 30 mg. The figures are clear enough; the question is what they mean and what they do not. I can supply the numbers if the specifics change the…
Conditions: semaglutide · PIONEER-1. I want to know whether this is a real physical effect or an artefact of how it is measured. What prompted the question is an…
The particulars: reflux · ecnoglutide · STEP 1. I have the document in front of me and I can read the numbers. What I cannot do is interpret them. I am reasonably…
Conditions: REDEFINE-1 · fatigue. I would like to know the limits of what can be inferred from this. What I am trying to avoid is over-reading a single result, which…
Stated plainly: retatrutide · semaglutide. Both of these get recommended confidently by different people, which suggests neither is obviously right. My constraints…
What I am working with: orforglipron · PIONEER-1. I keep seeing this stated as a fact with no explanation attached, and unexplained facts make me suspicious. My…
What I am working with: retatrutide · minus 20 °C. This has the shape of a fact but I cannot find its origin. What I found instead were three secondary sources all…
Concretely: SURMOUNT-2 · tirzepatide. The claim is plausible, which is exactly why I want to check it. I am able to read a paper if someone points me at one. Is there…
The particulars: SUSTAIN-6 · nausea. I have the document in front of me and I can read the numbers. What I cannot do is interpret them. I am reasonably comfortable…
Conditions: SURMOUNT-1 · 2 mg. I would like to know the limits of what can be inferred from this. What I am trying to avoid is over-reading a single result, which I…
What I have: STEP 2 · retatrutide. This is presented as though it settles something, and I am not convinced it does. I have two documents that appear to disagree,…
What I am working with: SURMOUNT-4 · reflux. I would like help reading this properly rather than being told what conclusion to reach. I have the full report including…
Setup, so nobody has to ask: dulaglutide · cagrilintide. I suspect the honest answer is that it depends, in which case I would like to know on what. Assume I can…
For reference: oral semaglutide · retatrutide. The comparison I want does not seem to exist anywhere in a form I can evaluate. I have read the arguments for each and…
Setup, so nobody has to ask: SELECT · a GLP-1 receptor agonist. I have read the primary source rather than the summary, which has left me with more questions. I…